Table 4.

Quintile analysis of dietary mutagen intake and risk of pancreatic cancer

	1*	2	3	4	5	Ptrend
MeIQx						0.14
Median (case/control)	7.46/7.61	19.42/18.98	35.33/32.60	57.82/55.43	129.77/129.48
Range (control)	0-13.96	14.13-25.26	25.41-43.64	44.11-78.67	79.34-679.06
No. (case/control)	138/106	95/106	107/106	120/106	166/106
OR†(95% CI)	1.00	0.62 (0.42-0.94)	0.73 (0.49-1.09)	0.81 (0.54-1.20)	1.11 (0.75-1.65)
DiMeIQx						0.02
Median (case/control)	0/0	0.78/0.85	1.74/1.80	3.08/3.02	7.63/7.15
Range (control)	0-0.34	0.35-1.31	1.31-2.26	2.27-4.03	4.04-33.60
No. (case/control)	115/107	127/105	91/107	109/105	184/106
OR (95% CI)	1.00	1.09 (0.73-1.62)	0.73 (0.48-1.10)	0.86 (0.57-1.30)	1.52 (1.03-2.25)
PhIP						0.22
Median (case/control)	20.10/24.22	64.67/61.48	111.68/118.44	219.76/221.54	496.88/431.48
Range (control)	0-41.63	41.64-84.41	84.78-158.64	158.93-304.99	305.1-2,667.07
No. (case/control)	127/106	92/106	138/106	127/106	142/106
OR (95% CI)	1.00	0.84 (0.56-1.27)	1.37 (0.92-2.02)	1.10 (0.74-1.64)	1.30 (0.87-1.94)
BaP						0.19
Median (case/control)	1.23/1.55	15.45/16.57	36.98/37.32	68.62/63.56	164.56/156.65
Range (control)	0-6.35	6.78-26.67	26.94-48.12	48.87-95.21	95.62-695.27
No. (case/control)	122/106	118/106	100/106	141/106	145/106
OR (95% CI)	1.00	0.93 (0.62-1.39)	0.80 (0.53-1.21)	1.35 (0.91-2.00)	1.32 (0.89-1.97)
Mutagenicity						0.10
Median (case/control)	1,419/1,676	3,342/3,392	5,427/5,465	9,119/8,716	18,611/17,006
Range (control)	0-2,433	2,459-4,332	4,340-6,794	6,903-11,920	11,934-76,495
No. (case/control)	125/106	105/106	109/106	131/106	156/106
OR (95% CI)	1.00	0.74 (0.49-1.11)	0.87 (0.58-1.30)	1.03 (0.70-1.54)	1.17 (0.78-1.76)

^*Quintiles of consumption from control group.

^†OR adjusted for age, race, sex, education, smoking, alcohol consumption, diabetes, pancreatitis, and family history of cancer.