. Author manuscript; available in PMC: 2007 Jun 15.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):655–661. doi: 10.1158/1055-9965.EPI-06-0993

Table 5.

Risk modification of dietary mutagen exposure and family history of cancer (FHxCA)

Variable^*	Case/con (n/n)	All	Negative FHxCA		Positive FHxCA		P_interaction
		OR^†(95% CI)	Case/con	OR (n/n; 95% CI)	Case/con (n/n)	OR (95% CI)
MeIQx(ng/day)
≤55.43	386/369	1.0	118/161	1.0	268/208	1.0
>55.43	235/159	1.48 (1.12-1.95)	100/74	1.95 (1.28-2.97)	135/85	1.17 (0.80-1.72)	0.16
DiMeIQx(ng/day)
≤3.02	421/395	1.0	119/167	1.0	302/228	1.0
>3.02	238/158	1.39 (1.05-1.83)	99/68	2.17 (1.41-3.34)	139/90	0.99 (0.68-1.94)	0.02
PhIP (ng/day)
≤221.54	421/370	1.0	139/171	1.0	282/199	1.0
>221.54	200/158	1.12 (0.85-1.48)	79/64	1.62 (1.05-2.50)	121/94	0.84 (0.58-1.21)	0.05
BaP (ng/day)
≤63.56	395/371	1.0	127/174	1.0	268/197	1.0
>63.56	226/157	1.51 (1.15-1.98)	91/61	2.32 (1.50-3.60)	135/96	1.16 (0.81-1.67)	0.02
Mutagenicity (revertants/g/day)
≤8,716	391/369	1.0	121/169	1.0	270/200	1.0
>8,716	230/159	1.41 (1.07-1.85)	97/66	2.06 (1.35-3.16)	133/93	1.00 (0.69-1.45)	0.03

The 60th percentile of the control value was used as the cutoff.

^†

OR adjusted for age, race, sex, education, smoking, alcohol consumption, diabetes, and pancreatitis.