Table II.
Rhodopsin Protein Reduction Following siRNA or Control Injection
| Vector | Right eyes, Rhodopsin protein | Left eyes, Rhodopsin protein | P value |
|---|---|---|---|
| siRNA301 | 40.4 ± 10.6 * | 100 ± 17.6 | <0.0127 |
| Irrelevant. siRNA | 125.7 ± 31.8 | 100 ± 10.7 | <0.445 |
Values (ratios of the intensity of the RHO band to the β-actin band in a Western blot) represent the content of rhodopsin protein in %. Experiment was done in triplicate. Right eyes were injected with either siRNA301 or irrelevant (phospholamban) siRNA. Left eyes were uninjected.