Table 2.
Substrate recurrence rate by medical conditions prior to ablation procedures
| 0 to 2 Months | 2 to 6 Months+ | 6 to 12 Months+ | 0 to 6 Months | 0 to 12 Months | |
|---|---|---|---|---|---|
| Total substrates | 7.0% (35/500) | 2.3% (10/427) | 1.7% (6/352) | 9.2% | 10.7% |
| Structural heart disease | |||||
| Congenital | 7.1% (1/14) | 9.1% (1/11) | 0.0% (0/9) | 15.6% | 15.6% |
| Cardiomyopathy | 0.0% (0/5) | 0.0% (0/5) | 0.0% (0/5) | 0.0% | 0.0% |
| Neither of above | 7.1% (34/481) | 2.2% (9/411) | 1.8% (6/338) | 9.1% | 10.7% |
| Echocardiogram shortening fraction (%) | |||||
| 1–30 | 6.1% (2/33) | 0.0% (0/28) | 0.0% (0/25) | 6.1% | 6.1% |
| 31–35 | 6.8% (10/146) | 3.2% (4/125) | 1.0% (1/98) | 9.8% | 10.8% |
| 36–40 | 7.3% (9/124) | 0.0% (0/104) | 2.3% (2/88) | 7.3% | 9.4% |
| >40 | 1.2% (1/85) | 2.6% (2/77) | 0.0% (0/64) | 3.7% | 3.7% |
| Unknown | 11.6% (13/112) | 4.3% (4/93) | 3.9% (3/77) | 15.4% | 18.7%a |
| Cardiac symptoms before procedure | |||||
| Palpitations | 5.5% (18/325) | 2.5% (7/275) | 1.8% (4/218) | 7.9% | 9.6% |
| Sustained tachycardia | 6.3% (22/349) | 2.3% (7/303) | 1.2% (3/252) | 8.5% | 9.6% |
| Syncope | 10.0% (4/40) | 0.0% (0/31) | 0.0% (0/26) | 10.0% | 10.0% |
| Chest pain | 3.9% (3/77) | 1.5% (1/65) | 0.0% (0/49) | 5.4% | 5.4% |
| Exercise intolerance | 6.7% (2/30) | 0.0% (0/20) | 5.9% (1/17) | 6.7% | 12.2% |
| Shortness of breath | 9.1% (4/44) | 2.9% (1/35) | 0.0% (0/28) | 11.7% | 11.7% |
| Other | 7.5% (5/67) | 3.7% (2/54) | 4.7% (2/43) | 10.9% | 15.0% |
| Indications for ablation | |||||
| Life-threatening arrhythmia | 2.9% (1/34) | 3.2% (1/31) | 0.0% (0/23) | 6.1% | 6.1% |
| Refractory to drug therapy | 7.5% (6/80) | 1.5% (1/66) | 1.8% (1/56) | 8.9% | 10.5% |
| Adverse drug effects | 14.3% (1/7) | 16.7% (1/6) | 0.0% (0/2) | 28.6% | 28.6% |
| Impending congenital heart disease surgery | NA (0/0) | NA (0/0) | NA (0/0) | NA | NA |
| Patient choice | 6.7% (25/374) | 2.2% (7/321) | 1.9% (5/268) | 8.7% | 10.4% |
| Cardiomyopathy | 25.0% (1/4) | 0.0% (0/3) | 0.0% (0/3) | 25.0% | 25.0% |
| Other | 0.0% (0/1) | NA (0/0) | NA (0/0) | NA | NA |
+
Substrates with recurrences at end of interval/substrates known not to have prior recurrence at beginning of interval.
a
Unknown echocardiogram shortening fraction vs known fraction, P < .05.