Skip to main content
. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Biol Psychiatry. 2006 Jul 3;61(3):348–358. doi: 10.1016/j.biopsych.2006.03.040

Table 6.

Lifetime co-morbidity (OR) of DSM-IV Eating Disorders with other core NCS-R/DSM-IV disorders and related behaviors1

Anorexia Nervosa Bulimia Nervosa Binge-eating Disorder Subthreshold Binge-eating Any binge-eating behavior
I. Anxiety disorders % OR (95% CI) % OR (95%CI) % OR (95% CI) % OR (95% CI) % OR (95%CI)
 Panic disorder 3.0 0.5 (0.1–2.7) 16.2 2.9* (1.1–7.9) 13.2 2.9* (1.8–4.8) 6.6 1.9 (0.7–5.4) 11.8 2.8* (1.8–4.3)
 Agoraphobia without panic 4.6 3.2 (0.6–17.8) 10.8 8.9* (3.0–26.2) 6.5 5.2* (1.9–13.9) 6.0 5.8* (1.5–22.1) 6.2 5.6* (2.4–12.9)
 Specific phobia 26.5 2.1* (1.0–4.3) 50.1 5.4* (2.6–11.4) 37.1 3.7* (2.2.–6.5) 20.7 2.0 (0.9–4.3) 32.5 3.3* (2.3–4.7)
 Social phobia 24.8 2.1 (0.9–5.2) 41.3 4.7* (2.7–8.3) 31.9 3.2* (2.1–4.9) 26.8 2.5* (1.5–4.3) 31.0 3.2* (2.4–4.3)
 Generalized anxiety disorder 7.0 1.0 (0.3–3.5) 11.8 1.9 (0.9–4.1) 11.8 2.0* (1.2–3.3) 9.9 2.3 (0.6–8.6) 11.9 2.2* (1.5–3.2)
 Post-traumatic stress disorder 12.0 1.6 (0.5–5.7) 45.4 10.2* (5.2–20.0) 26.3 5.1* (2.8–9.4) 5.6 1.1 (0.4–2.8) 20.2 4.0* (2.6–6.1)
 Obsessive-compulsive disorder3 0.0 17.4 7.5* (1.7–37.5) 8.2 4.2* (1.4–12.8) 0.0 7.2 4.6* (1.7–12.9)
 Separation anxiety disorder 7.5 1.7 (0.4–6.3) 15.7 3.5* (1.4–9.0) 12.2 3.3* (1.7–6.3) 2.6 0.8 (0.2–3.5) 9.7 2.7* (1.6–4.8)
 Any anxiety disorder4 47.9 1.9 (0.9–4.1) 80.6 8.6* (3.4–21.6) 65.1 4.3* (2.6–7.1) 40.4 2.0 (1.0–4.0) 59.5 3.7* (2.5–5.5)
II. Mood disorders
 Major depressive disorder 39.1 2.7* (1.3–5.7) 50.1 4.3* (1.7–10.8) 32.3 2.2* (1.3–3.7) 17.7 1.3 (0.6–2.7) 30.9 2.2* (1.6–3.2)
 Dysthymia 12.8 4.5* (1.2–17.1) 12.7 4.4* (1.5–12.6) 9.6 3.6* (1.9–6.9) 5.5 2.9 (0.9–9.0) 9.1 3.8* (2.4–6.1)
 Bipolar I-II disorders 3.0 0.8 (0.2–3.7) 17.7 4.7* (2.1–10.8) 12.5 3.6* (2.1–6.3) 10.5 3.0 (0.9–9.8) 12.0 3.5* (2.0–6.1)
 Any mood disorder 42.1 2.4* (1.2–4.7) 70.7 7.8* (3.6–16.8) 46.4 3.1* (1.9–4.8) 28.2 1.8 (0.8–3.9) 44.0 3.0* (2.1–4.3)
III. Impulse-control disorders
 Intermittent explosive disorder 4.7 1.0 (0.1–8.6) 3.6 0.7 (0.1–5.6) 9.4 2.2* (1.0–4.6) 5.4 1.0 (0.2–4.1) 7.2 1.5 (0.8–3.1)
 Attention-deficit/hyperactivity disorder2 16.2 2.1 (0.5–9.7) 34.9 8.4* (3.1–22.6) 19.8 3.1* (1.5–6.2) 10.7 1.3 (0.5–3.8) 19.0 3.0* (1.7–5.4)
 Oppositional-defiant disorder2 10.5 1.4 (0.2–8.1) 26.9 5.1* (2.1–12.5) 18.9 2.9* (1.4–6.3) 6.9 0.9 (0.2–3.5) 15.6 2.4* (1.3–4.3)
 Conduct disorder2 9.8 1.2 (0.2–6.7) 26.5 4.7* (2.0–10.8) 20.0 2.6* (1.4–4.8) 7.0 0.5 (0.1–2.2) 17.2 1.9 (1.0–3.8)
 Any impulse-control disorder2 30.8 1.4 (0.4–5.3) 63.8 6.7* (3.0–15.2) 43.3 2.5* (1.4–4.6) 22.3 0.8 (0.4–1.7) 40.2 2.2* (1.3–3.5)
IV. Substance use disorders
 Alcohol abuse or dependence 24.5 2.9* (1.2–7.2) 33.7 4.6* (2.1–10.5) 21.4 2.2* (1.2–4.0) 30.0 2.3 (1.0–5.6) 25.8 2.6* (1.9–3.7)
 Alcohol dependence 12.3 3.0* (1.3–7.0) 22.7 6.3* (2.3–17.3) 12.4 2.7* (1.1–6.7) 21.4 4.1* (1.4–11.8) 15.7 3.5* (2.1–5.8)
 Illicit drug abuse or dependence 17.7 3.4* (1.3–8.4) 26.0 5.3* (1.6–17.6) 19.4 3.4* (1.9–6.1) 22.9 2.9* (1.3–6.4) 20.2 3.4* (2.2–5.2)
 Illicit drug dependence 5.2 2.2 (0.4–12.5) 15.0 8.0* (1.5–43.7) 10.6 4.9* (2.2–11.3) 13.5 4.5* (1.5–13.5) 11.0 4.9* (2.8–8.7)
 Any substance use disorder 27.0 3.0* (1.2–7.1) 36.8 4.6* (2.0–10.8) 23.3 2.1* (1.2–3.8) 35.5 2.8* (1.2–6.5) 28.7 2.8* (1.9–3.9)
V. Any disorder
 Any disorder 56.2 1.3 (0.6–3.1) 94.5 17.6* (4.5–68.4) 78.9 4.2* (2.2–7.9) 63.6 2.0 (0.8–4.6) 76.5 3.7* (2.3–6.2)
 Exactly one 8.4 0.5 (0.1–1.8) 6.1 2.8 (0.7–11.7) 20.2 2.7* (1.1–6.5) 9.4 0.7 (0.2–2.5) 15.9 1.9 (1.0–3.8)
 Exactly two 14.1 1.4 (0.5–4.5) 24.0 19.2* (4.2–88.6) 9.8 2.2* (1.0–4.6) 23.5 3.2* (1.0–10.0) 15.7 3.2* (1.6–6.5)
 Three or more 33.8 2.3 (0.9–5.4) 64.4 33.7* (8.7–131.1) 48.9 7.6* (4.0–14.5) 30.7 2.6* (1.1–5.9) 45.0 6.4* (3.9–10.5)
*

Significant at the .05 level, two-sided test.

1

A separate logistic regression equation was estimated for each comorbid disorder and a single equation was estimated for number of comorbid disorders. Each equation controlled for respondent age (in five-year intervals), sex, and race-ethnicity.

2

Restricted to respondents in the age range 18–44 (n=1672)

3

Restricted to a random sub-sample of respondents (n=1139)

4

OCD was coded as absent among respondents who were not assessed for this disorder.