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. Author manuscript; available in PMC: 2007 Jun 15.
Published in final edited form as: Biochemistry. 2006 Nov 28;45(47):14223–14231. doi: 10.1021/bi061677n

Table 2.

Comparison of mcfp-4 Domain Repeats with Known His-and Asp/Glu-Rich Repeats Detected in Other Proteins

protein consensus sequence (no. of repeats) metal implicated ref
Mcfp-4 HQVLHGHVH (36) Cu this study
HMW kininogen GH (12) R/KH (6) Zn 36
HR glycoprotein GHHPH (12) Zn 37, 38
SR HCP HRHRGH (9) ? 39
prion protein PHGGGWGQ (4) Cu 23, 40
nodulin GH (10) ? 41
PfHRP 2 AHHAHHAAD (21) Fe-heme 28, 42
Mcfp-4 DDHVN(D/N)IAQIA (16) Ca this study
SR HCP EEEDEDDDEGD (9) Ca 38
frustulin CEGDCD (5) Ca 43
EF hand DKNGDGxxxxxE Ca 44