TABLE 2.
Serum IL-6a in young and aged mice given burn injury or intraperitoneal LPS | ||||
---|---|---|---|---|
Burn Model | LPS Model | |||
Sham | Burn | Saline | LPS | |
Young | n.d.c | 151 ± 25 | n.d. | 37 ± 27 |
Aged | 116 ± 37 | 298 ± 73b | 32 ± 9 | 5151 ± 3000b |
Values are expressed as mean IL-6 pg/ml ± standard error. Twenty-four hours after young and aged mice were given a 15% total body surface area scald, a sham injury, an intraperitoneal injection of LPS (1.5 μg/g body weight), or saline. blood was collected by cardiac puncture and serum assayed for IL-6 by ELISA. Data are shown as mean IL-6 pg/ml ± SEM. N = 8-12 mice per group.
p< 0.05 from all other groups.
n.d. = not detectable