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Epicardial coronary diameter changes with NG-monomethyl-L-arginine (L-NMMA) and glyceryl trinitrate (TNG) in the proximal and the distal coronary segments. L-NMMA caused significant vasoconstriction in the proximal and distal segments. Glyceryl trinitrate caused significant endothelium independent vasodilatation in the proximal and distal segments. *p < 0.05, †p < 0.001 v baseline.
