Figure 4  .

Percentage changes in coronary blood flow and coronary vascular resistance with bradykinin before (empty circles) and after (filled circles) N^G-monomethyl-L-arginine (L-NMMA) infusion. Bradykinin caused significant increases in coronary blood flow and decreases in coronary vascular resistance in a dose dependent manner before and after L-NMMA infusion (p < 0.001, respectively). These effects of bradykinin on coronary blood flow and coronary vascular resistance before and after L-NMMA infusion did not differ significantly.