Table 2.
Comparison of Individual Histological Features of the Tumours in Relation to Country of Origin and HPV Status
| HPV status | Chinese N = 16 | Australian N = 67 | ||||||
|---|---|---|---|---|---|---|---|---|
| Negative N = 16 | Total N = 67 | Negative N = 36 | Positive N = 31 | |||||
| Tumor differentiation* | ||||||||
| Well | 31% | 10% | 8% | 13% | ||||
| Moderate | 31% | 55% | 61% | 48% | ||||
| Poor | 38% | 34% | 31% | 39% | ||||
| Predominant growth pattern | ||||||||
| Sheet | 56% | 33% | 31% | 35% | ||||
| Nest | 44% | 6% | 9% | 3% | ||||
| Island | 0% | 38% | 40% | 35% | ||||
| Mixed | 0% | 23% | 20% | 26% | ||||
| Amount of extracellular keratin | ||||||||
| Mild | 75% | 59% | 46% | 74% | ||||
| Moderate | 19% | 24% | 34% | 13% | ||||
| Abundant | 6% | 17% | 20% | 13% | ||||
| Nuclear pleomorphism | ||||||||
| Mild | 19% | 5% | 3% | 6% | ||||
| Moderate | 44% | 61% | 74% | 45% | ||||
| Severe | 38% | 35% | 23% | 48% | ||||
| Mitotic counts | ||||||||
| Mean (range) | 16.19 (5–49) | 14.3 (2–57) | 12.0 (2–21) | 16.8 (2–57) | ||||
*, differentiation according to World Health Organization criteria for SCC of aerodigestive tract. 23