Table 2.
Transmission of Serially Diluted Brain Homogenate from MM1-sCJD (H-3)
| Dilution rate of the inoculum | Incubation periods* (days ± S.D.) | Occurrence (diseased/inoculated) |
|---|---|---|
| 10−1 | 141 ± 9.2 | 7/7 |
| 10−2 | 153 ± 7.3 | 4/4 |
| 10−3 | 198 ± 12.3 | 5/5 |
| 10−4 | 243 ± 58.5 | 5/5 |
| 10−5 | 269, 269 | 2/5 |
| 10−6 | 348 | 1/5 |
| 10−7 | >377 | 0/6 |
| 10−8 | >377 | 0/6 |
*Incubation periods: Means ± SD days from the inoculation to the development of disease.