Table 2.
Transmission of Serially Diluted Brain Homogenate from MM1-sCJD (H-3)
Dilution rate of the inoculum | Incubation periods* (days ± S.D.) | Occurrence (diseased/inoculated) |
---|---|---|
10−1 | 141 ± 9.2 | 7/7 |
10−2 | 153 ± 7.3 | 4/4 |
10−3 | 198 ± 12.3 | 5/5 |
10−4 | 243 ± 58.5 | 5/5 |
10−5 | 269, 269 | 2/5 |
10−6 | 348 | 1/5 |
10−7 | >377 | 0/6 |
10−8 | >377 | 0/6 |
*Incubation periods: Means ± SD days from the inoculation to the development of disease.