Table 2.

Acquisition of Subcutaneous Growth Properties of QR-32 Tumor Cells Injected after Admix with Early-Phase of Gelatin Sponge-Infiltrated Inflammatory Cells

No. of QR-32 cells	Inflammatory cells obtained from	No. of mice with tumor/no. of mice injected*			Mean survival time
		Exp. I	Exp. II	Total
1 × 105	-	0/10	0/10	0/20 (0%)	-
1 × 105	Day 5 gelatin sponge	6/12	5/10	11/22† (50%)	51.8 ± 5.3
1 × 105	Day 10 gelatin sponge	2/12	3/10	5/22‡ (23%)	53.4 ± 6.8
1 × 105	Day 20 gelatin sponge	1/12	0/10	1/22§ (5%)	53
1 × 105	Day 30 gelatin sponge	NA	NA	NA	NA
1 × 105	Neutrophils purified from bone marrow	1/10	1/19	2/19§ (11%)	58.5 ± 7.8

*Gelatin sponge was inserted into the subcutaneous space of mice. The sponge was removed as indicated days and infiltrated cells were collected. QR-32 cells (1 × 10⁵ cells) were admixed with or without 1 × 10⁶ cells of gelatin sponge-infiltrated cells or neutrophils obtained from bone marrow, and then injected subcutaneously into mice.

^†P < 0.001;

^‡P < 0.05;

^§not significant versus QR-32 cells alone.