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Overview of Changes in VEGF-A and HIF Immunohistochemistry and in Situ Hypoxia
| Early (day 3 after FA) | Late (day 14 after FA) | |
|---|---|---|
| VEGFA | General decrease | Recovery in regenerated tubules, low in fibrotic areas |
| HIF-1α | General decrease | General decrease |
| HIF-2α | General increase | General increase |
| In situ hypoxia | General increase | Increase in regenerated tubules |
Changes refer to histological observations in the renal cortex of experimental versus time-matched sham groups.
