Table 4.

NO Generation by Macrophages from Control and Nephritic Rats after Second Injection of OX7

NO generation in umol/ml	Spontaneous	IFN-γ + TNF (20 U + 10 ng/ml)	IL-4 (8 ng/ml)	TGF-β1 (10 ng/ml)
Control	3.9 ± 0.6	18.49 ± 1.8*	3.48 ± 1	3.22 ± 1.1
1 hour	23.95 ± 3.7	34.63 ± 0.9†	23.55 ± 3.6	27.37 ± 4.1
4 hours	34.62 ± 2.8	47.1 ± 1.2†	33.1 ± 1.3	35.67 ± 2

N = 6 for control rats and N = 4 for nephritic rats; mean ± SD.

*P < 0.05 compared with untreated controls.

^†P < 0.05 compared with macrophages from untreated nephritic rats.