Table 6.

Mutations in the MT Isoforms of the Amplified Products

Product	Cell line	Codon region	Mutation	Amino acid change
MT-1A	All	49	ATA → ATC	No
MT-1E	Myoepithelial	48	TGC → TGT	No
MT-1G	Myoepithelial	10	GGT → GCAGGT	Gly → Ala Gly
		46	CAA → CAG	No
		3′ UTR
		50*	T → C	No
MT-1H	All	5′ UTR
		19†	A → G	No
		22†	T → G	No
		8	GAG → GCC	Glu → Ala
		10	GGT → GGA	No
		13	TGC → TAC	Cys → Tyr
		50	TGC → CGC	Cys → Arg
		53	GCG → GCT	No
		54	TCA → TCG	No
		55	GAG → GAA	No
		3′ UTR
		10*	A → T	No
		19*	G → C	No
		22*	A → G	No
		47*	A → G	No
MT-1X	All	39	GTC → GTG	No

Mutated nucleotides and amino acids are shown in bold.

*Nucleotide distance from stop codon.

^†Nucleotide distance from start codon.

UTR; Untranslated region; Gly; glycine; Ala; alanine; Cys; cysteine; Tyr; tyrosine; Arg; arginine; Glu; glutamic acid.