Skip to main content
. 2003 Nov;163(5):1961–1968. doi: 10.1016/S0002-9440(10)63554-7

Table 2.

Blockade of IL-12 Decreases LPS-Induced Leukocyte Infiltration

Group n Total serum IgE (μg/ml) Peribronchial eosinophils (cells/20 HPF) Bronchoalveolar lavage
Total leukocytes (cells/HPF) PMN (%) Eosinophils (%) Lymphs (%)
No LPS + NRS 7 4.1 ± 0.7* 125 ± 44 17 ± 1 48.3 ± 6.1 5.9 ± 2.6 1.7 ± 0.4
15 μg LPS + NRS 7 3.8 ± 0.4 40 ± 12 70 ± 4 86.8 ± 5.6 0.4 ± 0.2 1.0 ± 0.3
15 μg LPS + aIL-12 9 5.5 ± 0.9 70 ± 13 46 ± 3 79.6 ± 4.6 1.0 ± 0.2 1.2 ± 0.4

*Data are combined mean ± standard error from two separate experiments.

Statistically significant difference (P < 0.05) compared to no LPS control.

Statistically significant difference compared to LPS + NRS group.