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. 2003 Nov;163(5):1859–1871. doi: 10.1016/S0002-9440(10)63545-6

Table 1.

Examples of Identified Shared Peptide Motifs and Homologous Proteins

Peptide motifs and their homologous protein sequence Frequency* P2† Protein containing the motif Protein description Accession number
    46 GPSKSCG51 9.7% <0.00000001 Chymase I Serine protease, convertase AB00823
            CAPGPSKSCG‡     for angiotensin II generation
            CTPYPSKSCG
            CSQYPSRSCG
            CLMTPSKRCG
140 CEEGWRLKCG150 4.9% <0.000001 Novel protein Interferon-induced protein with BC003804
            CQEPTRLKCG     tetratricopeptide repeats
            CKEPTRAHCG
    40 PPPGTRH46 3.6% <0.0001 Mouse-expressed Unknown AA960387
            CPHPGTRHC§     protein
            CTNTGHRHC
499 FFSRSC504 3.5% <0.00001 Ricken mouse Unknown AAH21390
            CEHFFSRSC cDNA
            CPGKISRSC 1300017J01 gene
            CSQYPSRSC
    85 LNNSQAH91 2.6% <0.0001 Hypothetical protein Unknown XP_091658
            CLNNSQAHC∥
            CPNNKSASC
139 ACLKMRLE146 2.6% ND** Sec23 homology Homologous to yeast-secreted I60247
            ACTKMRLEC     protein 23
321 ACMNQ325 2.6% <0.0001 AMP deaminase 3 Generating inosine NM_009667
            ACMNQRVQNC     monophosphate, regulate
            ACMNQTPDLC     neutrophil activity
            ACTNQFLQQC
145 NQRH-QMSC152 1.8% ND TIMP-2 Tissue inhibitor of 042146
            NQRH-QMSC     metalloproteinase 2
            NHRYMQM-C

*Frequency represents the prevalence of each peptide motif with >55% identity in the peptide data set as calculated based on Clustal W analysis.

†P value is the probability of the shared peptide motif occurring as a random event.

‡Four peptides with this sequence were selected.

§Three peptides with this sequence were selected.

para; and

∥, Two peptides with this sequence were selected.

**Not done.