Table 4.
Representative Marker Genes
| Tumor class | Select marker genes |
|---|---|
| Solid | Keratins 8, 18, and 19; collagen, type 1, alpha 2 |
| Hematolymphoid | CD37 antigen; T-cell receptor, beta cluster; lymphocyte cytosolic protein 1 |
| Mesothelioma | Keratins 5, 8, 18, 19; calretinin |
| Epithelial | Keratins 8 and 18; epithelial-specific transcription factor ESE 1b; mucin 1 |
| CNS | Growth/differentiation factor 1; calmodulin; kinesin family member 5 |
| Melanoma | S100 alpha and beta proteins; tyrosinase; differentiation antigen melan-A |
| Lymphoma | CD20 receptor; CD79 beta antigen |
| Leukemia | Terminal transferase; transcription factor ETR101 |
| Mullerian | Estrogen receptor; cellular retinol-binding protein |
| Non-Mullerian | Keratin 13; pulmonary surfactant-associated protein SP-A; carcinoembryonic antigen precursor |
| Ovary | Receptor of retinoic acid |
| Uterus | Hair keratin hHb6; alpha1 (XI) collagen |
| Breast | Estrogen receptor; androgen receptor; mucin 6; prolactin-induced protein |
| Prostate | Prostate specific antigen; prostatic secretory protein 57; prostatic acid phosphatase |
| Lung | Pulmonary surfactant-associated proteins A, B, C1 |
| Colon | Carcinoembryonic antigen precursor; trefoil factor 3; keratin 8 |
| Bladder | Keratins 13 and 17; Hep27 protein |
| Kidney | Insulin-like growth factor 2 |
| Pancreas | Mucin 5, subtype B; trefoil factor 1 |