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. 2003 Nov;163(5):1827–1837. doi: 10.1016/S0002-9440(10)63542-0

Figure 1.

Figure 1.

Genetic influence on CAIA susceptibility. A group of normal and B cell-deficient (B−) mice from several different strains were injected with two mAbs on day 0 and all of the mice received LPS on day 5. A: Incidence of antibody-induced arthritis. B: Arthritis severity was indicated as mean max score ± SEM. BALB/c (n = 36), B10.RIII (n = 36), B10.RIII (B−) (n = 17), QB (n = 61), QD (n = 34), QD (B−) (n = 7), B10.Q (n = 40), B10.Q (B−) (n = 14), C3H.Q (n = 15), C3H.Q (B−) (n = 4), DBA/1 (n = 19), DBA/1 (B−) (n = 5), C57BL/6 (n = 14), NFR/N (n = 6), RIIIS/J (n = 7), and NOD.Q (n = 11) mice were used in this experiment. Tlr4-deficient (n = 10) and BALB/c (n = 10) mice were injected with two mAbs on day 0. n indicates the number of mice in each group.