Table 1.
Characteristics of Patients with Juvenile Idiopathic Arthritis and Uveitis
Number of patients | 75 |
Median age at diagnosis of uveitis, yr (range) | 7 (1-36) |
Median age at diagnosis of arthritis, yr (range) | 5 (1-16) |
Gender | |
% female | 73.3 |
% male | 26.7 |
Race | |
% white | 84.9 |
% black | 6.9 |
Median duration of arthritis prior to presentation, yr (range) | 10 (1 month-52) |
Median duration of arthritis prior to diagnosis of uveitis, yr (range) | 1 (0-36) |
Median duration of uveitis prior to presentation, yr (range) | 6 (1 month-48) |
Bilateral uveitis, % | 70.7 |
Type of JIA | |
% Persistent oligoarticular (n) | 81.3 (61) |
% Systemic | 1.3 (1) |
% Polyarticular, RF negative | 6.7 (5) |
% Polyarticular, RF positive | 5.3 (4) |
% Enthesitis-related | 4.0 (3) |
% Psoriatic arthritis | 1.3 (1) |
Type of uveitis | |
% Anterior uveitis | 86.7 |
% Anterior and intermediate uveitis | 13.3 |
% ANA positive | 69.7 |
Median ANA titer (range) | 1:160 (1:10 - 1:640) |
Therapies prior to presentation | |
Oral corticosteroids, % | 35.1 |
Methotrexate, % | 18.7 |
Cyclosporine, % | 4.0 |
Periocular corticosteroid injection, % | 18.7 |
Therapies at presentation | |
Oral corticosteroids, % | 12.0 |
Methotrexate, % | 16.0 |
Cyclosporine, % | 2.7 |
Visual acuity, % | |
Better eye, 20/50 or worse | 18.7 |
Better eye, 20/200 or worse | 12.0 |
Eye-specific characteristics | |
Number of affected eyes | 132 |
Ocular findings at presentation, % | |
Band keratopathy | 31.5 |
Posterior synechiae | 27.5 |
Cataract | 22.5 |
Aphakic | 17.0 |
Pseudophakic | 6.1 |
Keratic precipitates | 15.4 |
Macular edema | 3.0 |
Epiretinal membrane | 3.8 |
Optic nerve edema | 4.5 |
Anterior chamber cell (≥ 0.5+) | 44.3 |
Anterior chamber flare (≥ 1+) | 49.0 |
Vitreous cell (≥ 0.5+) | 23.2 |
Ocular hypertension | 15.3 |
Hyptony | 9.3 |
Visual acuity at presentation, affected eyes, % | |
20/50 or worse | 36.4 |
20/200 or worse | 23.7 |
Surgeries prior to presentation | |
Cataract extraction | 26.7 |
YAG laser capsulotomy | 1.3 |
Band keratopathy chelation | 5.3 |
Trabeculectomy | 2.6 |
Tube shunt placement | 0.7 |
Laser peripheral iriditomy | 1.3 |
Vitrectomy | 7.3 |
ANA = antinuclear antibody; JIA = juvenile idiopathic arthritis; yr = years; (n) = number of patients with characteristic; (n/N) = number of eyes with characteristic/number of eyes at risk