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. 2007 Jun 15;3(6):e95. doi: 10.1371/journal.pgen.0030095

Figure 6. Modifier(s) in the Chromosome X of the CS- Indy206 Mutant Underlies Its Longevity.

Figure 6

Lifespan of Canton S (+/+) and long-lived CS- Indy206 males was analyzed on SY food in parallel with lines that no longer contain Indy206 mutation, but still retain Chromosome X or cytoplasmic constituents, including mitochondria and Wolbachia, from the CS- Indy206 strain. The strain that only retains cytoplasm from CS- Indy206 (and all nuclear chromosomes from wDah) shows similar lifespan compared with Canton S control (for both, median lifespan 53 d, Log-Rank test χ2 = 2.80, p = 0.0943). The strain that retains the Chromosome X from CS- Indy206 (and all other chromosomes plus cytoplasm from wDah) shows similar lifespan compared with long-lived CS- Indy206 (for both, median lifespan 64 d, Log-Rank test χ2 = 3.76, p = 0.0525). All other comparisons between the strains are significant (p < 0.0001).