Location of amino acids substitutions in GPC and NP proteins of ML29 reassortant. A non-conservative substitution, K272E, is located in the amino-terminal region of GP2 glycoprotein between GPC cleavage motif (RRLL, underlined) and the putative fusion peptide of arenaviruses (GGYCLTRWMLIEAELKCFGNTAV, underlined). A conservative mutation, N173S, is mapped to the central region of NP protein. A non-conservative substitution, A485D, is located in the carboxyl-terminal region of NP protein. GenBank accession numbers: ML29 reassortant, NC_006573; LAS-Josiah, NC_004296; LAS-GA391, X52400; LAS-CSF, AF333969; LASAV, AF246121; LCMV-ARM, NC_004294