. Author manuscript; available in PMC: 2007 Jun 18.

Published in final edited form as: Biochemistry. 2006 Oct 24;45(42):12654–12663. doi: 10.1021/bi061146z

Table 3.

Normal mode analysis of tACE and ACE2 - statistics for the mode having the highest overlap with the proposed structural transition for each structure studied.

Structure analysed	Comparison structure	Mode	Overlap	Collectivity	\|Amplitude\| (DQ^a)	RMSD^b (Å)
ACE2o	ACE2c	1	0.733	0.386	224	1.77
tACEo	tACEc	1	0.709	0.427	248	1.86
tACEo	wt tACE	1	0.643	0.427	245	2.19

ACE2c	ACE2o	2	0.117	0.132	85	3.43
tACEc	tACEo	6	0.133	0.500	96	3.62
wt tACE	tACEo	2	0.129	0.468	107	3.89

The relative amplitude of perturbation along the direction of the normal mode concerned, required to achieve the best alignment with the comparison structure; arbitrary units.

R.m.s. deviation for all Cα-atoms between the comparison structure and a model perturbed according to the mode in question and the stated amplitude.