. Author manuscript; available in PMC: 2008 Mar 1.

Published in final edited form as: Pharmacol Biochem Behav. 2007 Jan 31;86(3):550–558. doi: 10.1016/j.pbb.2007.01.018

Table 2.

Effect of pharmacological blockade of D₁ and D₂ receptors on CRF-induced deficits in %PPI (data shown as mean±SEM for 8 dB and 16 dB above background prepulse trials).

Prepulse Intensity	8 dB		16 dB
	Vehicle	CRF^*	Vehicle	CRF
Vehicle	47±7	39±9	62±6	64±7
Haloperidol	58±6	38±7	67±4	64±4
Vehicle	47±9	33±6	62±7	59±6
SCH23390^**	63±6	49±6	76±3	73±3

Main effect of CRF on PPI at 8 dB above background trials in both Haloperidol and SCH23390 studies.

^**

Main effect of SCH23390 treatment (see text for details).