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. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Nucl Med Biol. 2007 Feb;34(2):129–139. doi: 10.1016/j.nucmedbio.2006.12.002

Figure 2.

Figure 2

Competitive studies of [125I]7 in rat brains in vivo. Rats were pretreated with drugs with a dose of 2 mg/kg, iv. 5 min prior to the tracer administration. At 4 hr after the tracer injection, hypothalamus/cerebellum (HY/CB) ratios were compared between saline-pretreated (control) and drug-pretreated rats. The values are presented as the average ± SD of three rats in each point. (+)McN5652, Escitapram and ADAM (2) are serotonin transporter (SERT) ligands. Nisoxetine is a norepinephrine transporter (NET) ligand and GBR-12909 is a dopamine transporter (DAT) ligand.