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. Author manuscript; available in PMC: 2008 Apr 30.
Published in final edited form as: Diabetes Res Clin Pract. 2006 Oct 2;76(2):177–186. doi: 10.1016/j.diabres.2006.09.012

Table 1.

IGF-IGFBP axis profile in adults with DN vs. healthy people and diabetic patients without DN

Serum levels Urine levels
IGF-I ↓ H; ↑ DM ↑ DM
IGF-II ND ND
IGFBP-1 ↑ H ND
IGFBP-2 ND ND
IGFBP-3 ↓ H, DM ↑ DM
IGFBP-4 N for H ND
IGFBP-5 ↓ H ND
IGFBP-6 ND ND

H, healthy people; DM, diabetes without nephropathy; N, normal level; ND, no data in available literature.