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. Author manuscript; available in PMC: 2007 Jun 19.
Published in final edited form as: Psychopharmacology (Berl). 2006 Nov 10;190(1):51–63. doi: 10.1007/s00213-006-0594-x

Table 1.

Semi-quantification of DβH-positive fiber loss in various brain regions (see Paxinos and Watson 1998)

Anterior from bregma (mm) Brain region DBH-positive fiber loss
+5.20 FrA Frontal association +
MO Medial orbital cx ++
DO Dorsal orbital cx ++
LO Lateral orbital cx +
+4.70 FrA Frontal association cx +
PrL Prelimbic cx +++
MO Medial orbital cx +++
VO Ventral orbital cx ++
LO Lateral orbital cx +
DLO Dorsolateral orbital cx +
+4.20 M2 Motor cx 2 +
PrL Prelimbic cx +++
MO Medial orbital cx +++
VO Ventral orbital cx ++
LO Lateral orbital cx +
DLO Dorsolateral orbital cx +
+3.70 M1 Motor cx 1 +
M2 Motor cx 2 +
Cg1 Cingulate cx area 1 +++
PrL Prelimbic cx +++
MO Medial orbital cx +++
VO Ventral orbital cx +
LO Lateral orbital cx +
AI Agranular insular cx 0
+3.20 M1 Motor cx 1 +
M2 Motor cx 2 ++
Cg1 Cingulate cx area 1 +++
PrL Prelimbic cx +++
IL Infralimbic cx +++
VO Ventral orbital cx +
LO Lateral orbital cx 0
AI Agranular insular cx 0
+2.70 S1 Somatosensory cx +
M1 Motor cx 1 ++
M2 Motor cx 2 ++
Cg1 Cingulate cx area 1 +++
PrL Prelimbic cx +++
IL Infralimbic cx +++
DP Dorsopenduncular cx +++
VO Ventral orbital cx 0
LO Lateral orbital cx 0
AI Agranular insular cx 0
+2.20 S1 Somatosensory cx +
M1 Motor cx ++
M2 Motor cx ++
Cg1 Cingulate cx area 1 +++
PrL Prelimbic cx +++
IL Infralimbic cx +++
DP Dorsopenduncular cx +
CPu Caudate putamen 0
NAc Nucleus accumbens 0
+1.70 S1 Somatosensory cx +
M1 Motor cortex 1 +
M2 Motor cortex 2 +
Cg1 Cingulate cx area 1 +
Cg2 Cingulate cx area 2 +
CPu Caudate putamen 0
NAc Nucleus accumbens 0
+ 1.20 S1 Somatosensory cx +
M1 Motor cx 1 +
M2 Motor cx 2 +
Cg1 Cingulate cx area 1 +
Cg2 Cingulate cx area 2 +
AI Agranular insular cx 0
CPu Caudate putamen 0
NAc Nucleus accumbens 0
S/DB Septum/Diagonal band 0
+0.70 S1 Somatosensory cx +
M1 Motor cx 1 +
M2 Motor cx 2 +
Cg1 Cingulate cx area 1 +
Cg2 Cingulate cx area 2 +
CPu Caudate putamen 0
NAc Nucleus accumbens 0
S/DB Septum/Diagonal band 0

0 No loss, + minor loss, ++ substantial (about 50%) loss, +++ total loss of fibers in DβH–saporin rats compared to sham animals, cx cortex