Table 1.
Simple summary of the effects of lesions to different brain regions on various tests of impulsivity in the rat
| Region | Stop-task | Delay-discounting | 5CSRT |
|---|---|---|---|
| PRL | ↔ | ↔ | ↔ |
| IL | ? | ↔ | ↑ |
| ACx | ? | ↔ | ↑ |
| OFC | ? | ↓ | ↑ |
| NAC | ↔ | ↑ | ↑ |
| Medial striatum | ↑ | ? | ↑ |
| STN | ? | ↓ | ↑ |
↔: no effect on performance; ↑: increase in impulsive behavior; ↓: decrease in impulsive behavior; ?: effects unknown. Abbreviations: 5CSRT five-choice serial reaction time task; PrL prelimbic cortex; IL infralimbic cortex; ACx anterior cingulate cortex; OFC orbitofrontal cortex; NAC nucleus accumbens; STN subthalamic nucleus.