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. 2000 Dec 12;97(26):14388–14393. doi: 10.1073/pnas.011513398

Figure 1.

Figure 1

Expression of mRNAs for cystatin B and tag 123 in WT and Otx2−/− embryos at 6.5 and 7.5 dpc, and comparison to the Otx2 transcription domain. Values at the lower right hand corner of A, B, E, and F show tag abundance in the two libraries. The black arrowheads point to the embryonic–extraembryonic junction. (A and E) Expression of mRNAs for cystatin B and tag 123 in 6.5 dpc WT embryos. (B and F) Expression of mRNAs for cystatin B and tag 123 in 6.5 dpc Otx2−/− embryos. (G and H) Expression of mRNA for tag 123 in 7.5 dpc embryos. (C and D) β-galactosidase staining of Otx2+/− and Otx2−/− embryos carrying a LacZ reporter gene in the Otx2 locus. (Scale bar: 100 μm.)