Table 3.
Reporter metabolites around which most significant gene expression changes occurred in response to overexpression of NADH oxidase or alternative oxidase in S. cerevisiae
| Reporter metabolites | P value* |
|---|---|
| In response to NADH oxidase | |
| NADH | 5.38E-09 |
| NAD | 2.18E-08 |
| sn-glycerol 3-phosphate | 3.16E-03 |
| 3-phosphonooxypyruvate | 3.98E-03 |
| NADH–mitochondrial | 5.17E-03 |
| Acetaldehyde–mitochondrial | 6.06E-03 |
| 3-phospho-d-glyceroyl phosphate | 9.18E-03 |
| Acetaldehyde | 9.50E-03 |
| In response to alternative oxidase | |
| NADH–mitochondrial | 7.48E-08 |
| NAD–mitochondrial | 6.20E-05 |
| Orotate | 1.37E-03 |
| CoA–mitochondrial | 1.53E-03 |
| Oxaloacetate–mitochondrial | 2.23E-03 |
| Acetaldehyde–mitochondrial | 2.50E-03 |
| Oxygen–mitochondrial | 2.85E-03 |
| 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone–mitochondrial | 2.85E-03 |
* Probability that normalized transcription activity around a metabolite is the same as that in the background.