Fig. 6.

Regression analysis between brain activity and estradiol/progesterone levels during the luteal phase of the menstrual cycle. (Upper) During anticipation of uncertain rewards, progesterone level correlated positively with activity of the bilateral amygdalo-hippocampal complex and putamen. (Lower) Interactions between the effects of estradiol and progesterone levels on brain activity in the posterior orbitofrontal, anterior cingulate, and fronto-polar cortices, and amygdala at the time of the rewarded outcome. The graphs show such interactions in the right amygdala.