Fig. 5.

Phenotypic analysis of PbAQP-null parasites. (A) Uptake of [¹⁴C]glycerol into erythrocytes infected with WT parasites (open circles), erythrocytes infected with PbAQP-null parasites (triangles), or uninfected erythrocytes (squares). The uptake of radiolabeled glycerol was measured after 5, 10, 15, 30, 60, and 120 min of incubation. The data are representative of those obtained in two similar experiments. Standard deviations fall within the symbols. (B) Parasitemia of mice infected with WT parasites (circles) or PbAQP-null parasites (squares). Each value is the mean ± SEM. (C) Survival of mice infected with WT parasites (circles) or PbAQP-null parasites (squares).