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Obese phenotype in rats. (A) A representative photomicrograph of ERα immunoreactivity in the rat hypothalamus 3 weeks after unilateral injections with the indicated vectors. (B–H) Effects of bilateral vector infusions into the VMN of gonad-intact female rats on body weight (B), total adiposity (C), visceral to s.c. fat ratio (D), lean tissue mass (E), total energy expenditure (F), basal metabolic rate (G), and respiratory quotient (H). Data are means ± SEM (∗, P < 0.05).
