Consensus amino acid sequences. In D. melanogaster, the PF repeat appears to have arisen as a duplication of a more primitive repeat. The C-terminal half of this sequence is aligned beneath the N-terminal half of the D. melanogaster repeat and is labeled “c term.” There is a 14-amino-acid deletion in the PF repeat that has become fixed in D. simulans, D. sechellia, and D. mauritiana, and a 9-amino-acid deletion is fixed in the D. yakuba array. There are additional polymorphic additions and deletions not shown in the arrays from D. yakuba, D erecta, D. willistoni, D. mojavensis, and D. orena. Although the An. gambiae repeat is from a region adjacent to the Dumpy PF region, note that their amino acid compositions are similar.