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. Author manuscript; available in PMC: 2007 Jun 19.
Published in final edited form as: Oncogene. 2006 Jun 12;25(56):7421–7433. doi: 10.1038/sj.onc.1209729

Figure 8.

Figure 8

Reintroduction of p16 expression causes growth arrest and a senescent morphology in immortalized Strain C and A TERT-transduced HFKs transferred from co-culture with Feeders to Plastic. Late passage (PD>100) Strain C and A TERT Feeders to Plastic cells were infected with retrovirus carrying either pBABE-p16 or pBABE alone. Cells were incubated with BrdU before fixation and stained with antibodies to both p16 and BrdU. DAPI staining was performed for visualization of all HFK nuclei in the microscopic field. Strain A TERT/Feeders to Plastic #5 cells are represented above.