Figure 1.—

Correlations between the effects of mutations on different hosts. (A and B) The relationship between the fitness of mutant phage on the novel host glycinea and one of two standard hosts (phaseolicola or japonica). Data points are means of four replicate measures on host japonica and means of six replicate measures on hosts glycinea and phaseolicola. The solid lines are the mean value of the wild-type φ6 on the standard host and the dashed lines correspond to the value below which mutants are significantly lower in value than wild type (the LSD). (C) The relationship between fitness on the two standard hosts. To generate the data, fitness was measured using either a plaque size assay or a paired growth assay (relative growth rate, W). Plaque area increases linearly with log W.