TABLE 2.

Mosaic structure in influenza A hemagglutinin gene

								Dunn–Šidák
p	q	c	Null	Observed maximum	P-value	Observed maximum descent	P-value	Maximum	md
1979h	1961s	1918h	H148,159	7	0.45	46a	4.00 × 10−4		0.03
1961s	1979h	1918h	H159,148	39b	7.85 × 10−4	30c	5.22 × 10−3	0.05	NS
1979h	1961s	1930s	H94,218	0	1	124	1
1961s	1979h	1930s	H218,94	124	1	10d	9.06 × 10−3		NS
1979h	1961s	1984h	H92,220	0	1	128	1
1961s	1979h	1984h	H220,92	128	1	12e	8.88 × 10−4		0.06

The first three columns refer to the five influenza sequences mentioned in the Influenza A section. Here, the sequences are referred to by year and whether the sequence is human (h) or swine (s). The last two columns show the Dunn–Šidák corrected P-values given that without any knowledge about which sequences are recombinant, 60 comparisons would have to be made to test all parent–parent–child combinations. The breakpoint descriptions listed in footnotes a–e refer to a gapped alignment of length 1778 nt; 80 positions are gapped.

^aThere are 90 pairs of breakpoints that result in a maximum descent of 46 units in the diagrammed walk from these three sequences. The first breakpoint is in position 242–247, while the second one is in 953–955/971–982.

^bThe maximum height of 39 for this triple can be attained by 15 different breakpoints, at positions 952–954/970–981.

^cThere are 30 pairs of breakpoints that result in a maximum descent of 30 for this sequence triple. The first breakpoint is in position 953–955/971–982; the second breakpoint is either in position 1653 or in position 1654.

^dThere are 45 pairs of breakpoints that result in a maximum descent of 10 for this sequence triple. The first breakpoint is in position 953–955/971–982; the second breakpoint is in position 1049–1051.

^eThere are 9 pairs of breakpoints that result in a maximum descent of 12 for this sequence triple. The first breakpoint is in position 953–955; the second breakpoint is in position 1049–1051.