TABLE 3.

Computation times (last four columns) for computing recombination statistics and P-values in large data sets

Data set	Segregating sites	No. sequences	P-value	Δm,n,2 (min)	MR-30,1	Chim-Sp	Chim-2006
Dengue E	618	69	3.3 × 10−5	2	86 min	24 min	∼100 hr
Human mtDNA	1079	262	4.6 × 10−3	6	∼180 hr	∼48 hr	∼550 days
Influenza HA	316	308	1	4	∼43 hr	9 hr	∼105 days

All times and estimates are for a single 3.2-GHz processor. Dengue data are serotype 2 from Holmes et al. (1999); human mitochondrial DNA sequences are a subset of distinct strains from Kivisild et al. (2006); influenza seqeunces are New Zealand H3N2 isolates from 2000–2005 analyzed in Boni (2007). The P-value reported in this table is the minimum P-value (testing with Δ_m,n,2) from all comparisons in a data set, corrected with a Dunn–Šidák correction.