Figure 2.

Physiological consequences of decreased corticosterone secretion in fasted SF-1 +/− mice. (a) Perirenal white adipose tissue (WAT) weight in fed and fasted SF-1 +/+ and +/− mice. Similar results were obtained for subcutaneous WAT (data not shown). (b) Plasma leptin levels reflected fat mass in SF-1 +/+ and +/− mice. (c) Plasma glucose levels in fed and fasted SF-1 +/+ and +/− mice. For all panels, n = 4 per group. Plasma insulin levels were significantly decreased in fasted mice compared with fed mice, but did not differ between genotype (data not shown). *, P ≤ 0.05 vs. wild type; **, P ≤ 0.01 vs. wild type.