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. 2000 Dec 19;97(26):14488–14493. doi: 10.1073/pnas.97.26.14488

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Copyright © 2000, The National Academy of Sciences

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Glucocorticoid-induced thymocyte cell death is absent in SF-1 +/− mice. FACS analysis of thymocytes from fed (a) and fasted (b) SF-1 +/+ and +/− mice using CD4-PE and CD8-FITC (n = 4 mice per group). A FACS analysis from one mouse of each group is shown with the percentage of CD4⁺CD8⁺ cells per total cells analyzed shown in the upper right corner of each graph. Data shown for the +/+ fasted mouse reflects the strongest response. The average number of CD4⁺CD8⁺ cells per total cells analyzed did not differ between fed SF-1 +/+ and +/− mice (+/+, 68.6 ± 2.0%; +/−, 71.3 ± 1.6%), but was significantly different between fasted groups (+/+, 33.1 ± 3.6%; +/−, 61.6 ± 2.0%; P = 0.013).