TABLE 1.
IAP element |
Gene |
||||||
---|---|---|---|---|---|---|---|
Transcript | Sizea (kb) | Type | Presence in C57BL/6 genome | Name | Orientationb | Transcription start sitec | Fusion transcriptd |
M63 | 7 | Full length | No | D14Ertd500e | Reverse | −56, −251 | ND |
M65 | 2 | Deleted | No | Ercc3 | Reverse | −20, −264, −558 | + |
M68 | 5.3 | Deleted | Yes | Kif24 | Reverse | −284 | ND |
M73 | 0.43 | Solitary LTR | Yes | Acly | Reverse | −8, +28 | ND |
M81 | 0.34 | Solitary LTR | No | Pcaf | Reverse | −55, −185 | ND |
M84 | 4 | Deleted | Yes | Suclg2 | Reverse | −363 | + |
M103 | 5 | Deleted | No | None | NA | −69, −173 | NA |
A11 | 0.52 | Solitary LTR | No | AK008696 | Reverse | −36, −65 | + |
A24 | 0.33 | Solitary LTR | Yes | Cyp20a1 | Reverse | −90 | + |
A25 | 7 | Full length | No | ENSMUSG00000025246 | Reverse | +155 | ND |
H8 | 5 | Deleted | Yes | Rpo1-4 | Reverse | +10, +73, −13, −223 | + |
Sizes of IAP elements not present in the C57BL/6 genome database were estimated by PCR amplification of IAP elements from the 129 mouse genome.
Orientation of IAP elements relative to the endogenous genes. NA, not applicable because of the absence of genes at the locus under study.
Transcription start sites were determined by sequencing 5′RACE reaction product and the distance from the end of the IAP–LTR is shown in nucleotides. Plus numbers represent the start sites mapped outside the IAP–LTR, and minus numbers represent the start sites mapped inside the IAP–LTR.
ND, not detected by PCR analysis; NA, not analyzed because of the absence of genes at the locus under study.