Figure 7.—

Overexpression of ttm50 in the compound eye causes extra proliferation of cells. (A) Scanning electron micrograph of wild-type eye. The number of ommatidia was 752.5 ± 23.5 (n = 13). (B) Rough-eye phenotype caused by overexpression of ttm50 under the control of the glass-mediated response element. (C) Suppression of rough-eye phenotype by a reduction by half in the gene dosage of hid grim reaper using the Df(3R)H99. (D) Suppression of rough-eye phenotype by a reduction by half in the gene dosage of hid alone. (E) Enhancement of rough-eye phenotype by a reduction by half in the gene dosage of DIAP. (F) Suppression of rough-eye phenotype by the co-expression of the caspase inhibitor p35. The number of ommatidia increased (798.5 ± 11.6, n = 13) significantly compared to wild type. Expression of p35 alone did not affect ommatidial organization or number (754.0 ± 10.8, n = 6) compared to wild type.