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Frequencies of the slow acetylator genotypes and phenotypes in HIV-positive patients with and without hypersensitivity to SMX, and in healthy volunteers.
| HIV-positive patients | |||
|---|---|---|---|
| NAT2 genotype/ phenotype | SMX- hypersensitive (n = 32) | SMX- nonhypersensitive (n = 8) | Healthy volunteers (n = 26) |
| Slow genotype | 20 (63%) | 3 (38%) | 18 (69%) |
| Slow phenotype | 17 (53%) | 3 (38%) | 17 (65%) |
NAT2, N-acetyl transferase type 2; SMX, sulphamethoxazole.
