Table 3.
Characterization of β tumor cell lines
| Cell line | NCAM expr.a | Col IV adhesionb | 2Dc | 3Dd | s.c.e | i.v.f |
|---|---|---|---|---|---|---|
| βT2 | +++ | + | + | +g | + | + |
| βTi(fl/fl) | + | + | + | + | + | + |
| βTN2 | − | +h | + | +g | − | + |
| βTi(Δ/Δ) | + | − | ± | − | − | − |
| NCAM expression levels of cell lines: +++, high levels; +, low levels; −, no expression. | ||||||
| Adhesion to collagen IV stimulatable by NCAM transfection: +, stimulatable; −, not stimulatable. | ||||||
| Growth of cell lines in 2D cultures: +, fast growth; ±, slow growth. | ||||||
| Growth of cell lines in Matrigel: +, growth; −, no growth. | ||||||
| Tumor growth after subcutaneous injection: +, tumors growth; −, no tumor formation. | ||||||
| Lung metastasis after intravenous injection: +, metastases; −, no metastases. | ||||||
| Data not shown. | ||||||
| Also shown in Cavallaro et al (2001). | ||||||