Figure 2.

Inhibition of HIV-1 RT° does not perturb routing to the nuclear membrane but results in stable perinuclear accumulation of viral CA. P4 cells were transduced with TRIP-GFP Flap+ vector in the presence or absence of 1 μM nevirapine, or were left nontransduced as control. Immunofluorescence images are a merge of four confocal stacks showing p24(CA) staining at 48 h p.i. Scale bar=5 μm.