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Locomotor dose-response to acute fluoxetine in DAT+/+, DAT+/−, and DAT−/− mice. Animals (n = 5) were injected with fluoxetine (5, 10, and 20 mg/kg, s.c.) or vehicle, and immediately placed in the activity boxes during 1 h. Locomotion was measured as the number of photocell beam breaks (mean ± SEM). * p<0.05 and ** p<0.01 vs. saline-treated mice (ANOVA followed by Tukey’s test).
