Table 1.
Clinical characteristics prior to and during study
Year HIV+ | HAART | Duration <50 copies/ml | CD4/μl (%) | VPA μg/ml | ||
---|---|---|---|---|---|---|
total | free | |||||
Pt. 1 | 1995 | TDF/ABC/D4T/APV/r | 38 mo* | 1285 (43%) | 65.1-83.1 | 5.8-6.7 |
Pt. 2 | 1999 | DDI/FTC/Efv | >43 mo† | 558 (26%) | 52.4-89.6 | 3.0-9.8 |
Pt. 3 | 1985 | TDF/ABC/3TC/Efv/Nfv | >24 mo†* | 350 (18%) | 56.7-81.0 | 3.9-6.8 |
Pt. 4 | 1995 | ZDV/3TC/Nvp | >75 mo† | 372 (35%) | 33.9-74.8 | 2.2-8.7 |
Viremia was suppressed prior to the first visit of these patients to our clinic.
Patient 1: single measurement of 71 copies/ml HIV-1 RNA at week −96. Patient 3 single measurements of 636 copies/ml at week −12, and 98 copies/ml at week −72.
ZDV: zidovudine, 3TC: lamivudine, Nvp: nevirapine, DDI: didanosine, FTC: emtricitibine, Efv: efavirenz, TDF: tenofovir, ABC: abacavir, Nfv: nelfinavir, D4T: stavudine, APV/r: amprenavir with low-dose ritonavir