Table 1.

HPV genotyping by DNA Sequencing v. Digene HC2 Test

PCR/DNA Sequencing			Test Results by Digene HC2
Type Positive Cases		Prevalence (%)	High-risk+	Negative
16	29	(27.2)	11	18
56	9	(8.5)	9	0
31	7	(6.5)	5	2
6	6	(5.6)	2	4
18	6	(5.6)	6	0
54	6	(5.6)	3	3
58	6	(5.6)	5	1
66	6	(5.6)	6	0
59	4	(3.7)	4	0
45	3	(2.8)	2	1
83	3	(2.8)	2	1
32	2	(1.9)	0	2
35	2	(1.9)	1	1
39	2	(1.9)	2	0
40	2	(1.9)	0	2
52	2	(1.9)	1	1
33	1	(0.9)	1	0
53	1	(0.9)	1	0
62	1	(0.9)	1	0
68	1	(0.9)	1	0
70	1	(0.9)	1	0
72	1	(0.9)	0	1
73	1	(0.9)	0	1
M16	1	(0.9)	1	0
M 16, 18	1	(0.9)	1	0
M others	3	(2.9)	1	2
Total	107	(100)	67	40
			HC2 HPV detection rate = 67/107 = 62.6%
Samples	513
%HPV+ 20.9

M16 = mixed infection with HPV 16 identified by type-specific sequencing primer.

M 16, 18 = mixed infection with HPV 16 and HPV 18 identified by type-specific sequencing primers.

M others = mixed infections by HPV types which cannot be sequenced with type-specific primers for HPV 6, 11, 16 or 18.

Digene High-risk + includes those cases reported as positive for both High-risk and Low-risk HPV types.

The underlined HPV genotypes are included in the "High-risk" Digene HC2 cocktail probe.