Table 3.
Baseline characteristics associated with response to antiviral treatment after multivariate logistic regression analysis a) of the whole cohort of patients b) of CHB patients c) of CHC patients (only variables with statistical significance are shown). Data are reported as median and range.
Total number of responders (n = 30) | Total number of non-responders (n = 20) | p-value | |
Leptin (pg/ml) | 4642.5 (917, 32879)* | 10733 (695, 43605) | 0.002 |
CHB patients | Responders to lamivudine monotherapy (n = 19) | Non-responders to lamivudine monotherapy (n = 6) | p-value |
Leptin (pg/ml) | 5334 (917, 17436) | 13111.5 (8844,43605) | 0.003 |
CHC patients | Sustained responders (n = 11) | Nonsustained responders (n = 14) | p-value |
Genotype 3 | 7 (63.6%) | 4/14 (28%) | 0.01 |