Table 3.

Combinatory effect of MAK-4 and MAK-5 on H-ras-induced transformation assessed by focus formation assay

Treatment	Exogenous H-ras gene	Cytoxicity (% survival)	Foci/plate ± SD	Relative number of foci
Mock control	-	100	0	-
None	+	100	81.7 ± 2.3	1.00
MAK-5, 500 μg/ml plus MAK-4, 0 μg/ml	+	65	25.3 ± 2.7	0.52
MAK-5, 500 μg/ml plus MAK-4, 100 μg/ml	+	81	17.7 ± 0.9	0.28
MAK-5, 500 μg/ml plus MAK-4, 200 μg/ml	+	88	20.3 ± 0.8	0.31

The experimental procedure and the duration of treatment was the same as Table 1.